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Published - Fri, 09 Sep 2022

Stages of Wound Healing

Stages of Wound Healing

1. Immediate response to tissue injury

— Vasoconstriction and tissue contraction occur.

— Platelets aggregate and a clotting cascade is activated.

— Once hemostasis is complete, the release of vasoactive amines causes capillary dilation, and an exudate forms.

2. Inflammatory phase

— Granulocytes and lymphocytes accumulate to control the growth of bacteria and prevent infection.

— Immunoglobulins contribute to the control of infection.

— Macrophages phagocytize debris, encourage collagen deposition, and stimulate neovascularization.

3. Epithelialization

— Within 12 hours of injury, cells of the stratum germinative are activated, and within 24 hours, initial epithelialization may be complete.

4. Neovascularization

— New blood vessels form and bring nutrients and oxygen to the healing wound.

— Neovascularization begins on day 3 and peaks on day 7.

— By day 21, the process is complete and the new blood vessels withdraw as the tissue matures.

5. Collagen synthesis

— Fibrocytes initially lay down a disorganized pattern of collagen.

— Over months to years, the matrix is remodeled to form an organized meshwork of collagen.

6. Wound contraction

— Myofibroblasts are responsible for wound contraction, in which the initial scar contracts to a smaller size.

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Rigomo Team

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Rigomo is an e-learning platform that was founded in 2019 by a team of dedicated professionals with a passion for revolutionizing the way people learn. The platform offers a range of online courses that cover various industries, including business, technology, healthcare, and more.

Rigomo's courses are designed to be interactive and engaging, with a focus on practical skills that learners can apply in their careers. The platform uses a combination of video lectures, quizzes, and hands-on projects to help learners master the subject matter.

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Since its launch, Rigomo has received numerous accolades for its innovative approach to e-learning. The platform has helped thousands of learners across the globe acquire new skills and advance their careers.

As Rigomo continues to grow, the team remains committed to providing high-quality education that is accessible to all. The platform is constantly updating its courses and features to ensure that learners have access to the latest tools and technologies.

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